RESEARCH COMMUNICATION Role of Preoperative Chemotherapy in Squamous Cell Carcinoma of Esophagus in Kashmir, a Cancer Belt - A Pilot Study

نویسندگان

  • Ghulam Nabi Lone
  • Ajaz Aziz Sheikh
چکیده

Esophageal cancer is one of the ten most common malignancies worldwide (Parkin et al., 1999). The Kashmir region because of its geographical location is a part of the so called “Asian Esophageal Cancer Belt” (Deshpande et al., 2000), which extends from the northern provinces of China in the east to the southern shores of Caspian Sea in the west. It is one of the most common malignancies seen in the Kashmir valley with incidence reported to be in the range of 43.6/1, 00,000 population (Khuroo et al., 1992). Surgery until recently was the mainstay in the management of esophageal cancer. However the long term

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Detection of Human Papillomavirus in Osophageal Squamous Cell Carcinoma samples in Mazandaran Province, Iran

We examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. All subjects live in Mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “Asian Esophageal Cancer Belt”. Samples were tested for HPV-DNA by MY09/11 and Gp5+/6+ general primers using nested PCR. Of the 170 ESCC samples, 86 (50.6%) were ma...

متن کامل

The Effect Of P53 Protein Over-Expression And Its Clinical Features On The Response To Preoperative Chemoradiotherapy Of Esophageal Squamous Cell Carcinoma

Background and Objective: P53 is a suppressive gene that plays a key role in DNA repair and apoptosis. The purpose of this study was to investigate the effect of P53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (SCC) response to neoadjuvant chemoradiotherapy. Patients and Methods: In this retrospective cohort study, 44 patients with loc...

متن کامل

بررسی اثرات 4 نوع عصاره میوه آووکادو بر روی رده سلول های اسکواموس کارسینوم مری در مقایسه با سلول های تک هسته ای خون محیطی و گروه کنترل

Background and purpose: The majority of patients with cancers of the digestive system admit themselves to the health care systems in the final stages of the disease and conventional treatments do not have a major impact on the prognosis in these patients. Therefore, utilization of new methods of treatment with lower adverse effects can cause higher survival rates. In this study, the in vitro ef...

متن کامل

Esophageal cancer: associated factors with special reference to the Kashmir Valley.

Esophageal cancer is one of the most common cancers worldwide. It is a multifactorial disease, and no single agent has been identified so far as the sole cause of the cancer. Many factors like smoking, the consumption of alcohol, fungal-contaminated, spicy and various nitrosamine-containing food stuffs and hot beverages, nutritional deficiency of some vitamins like β-carotene, vitamin A, C and ...

متن کامل

Detection of Human Papillomavirus DNA by PCR in Esophageal Squamous Cell Carcinoma from Turkmen Sahra, North-East of Iran

Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographical locations. In this study, neoplasms from Turkmen Sahra, a region in Golestan province in northeast part of Iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of HPV DNA. Turkmen Sahra is located in the cancer...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011